- Albert Einstein HealthCare Network - A private, not-for-profit organization with five major facilities and many outpatient centers. Located in Philadelphia.
- Conemaugh Health System - Serves west central Pennsylvania. Provides a full range of services including treatments and technologies related to heart, vascular, cancer, neuroscience, and women's care.
- Crozer-Keystone Health Systems - Includes Community Hospital, Crozer Chester Medical Center, Delaware County Memorial Hospital, Springfield Hospital at the Healthplex, Taylor Hospital and four facilities. Based in Pennsylvania.
- Geisinger Health System - Founded in 1915, the System provides more than two million people in 31 counties in Pennsylvania a complete continuum of quality health care. Includes information about the system and the numerous services provided. (Danville)
- Health Network of the Chester County Hospital - Provides up-to-date news, publications, directions, program and services information, a calendar, plus a search site for physicians. (Pennsylvania)
- Heritage Valley Health System - Provides comprehensive health care for residents in southwestern Pennsylvania, eastern Ohio, and northern West Virginia. Based in Beaver, PA.
- Jefferson Health System - An alliance of numerous health care facilities serving the greater Philadelphia region. Information on the members of the System, health related resources, find a doctor and community resources.
- Saint Vincent Health System - Group of hospitals and medical centers based in Erie with locations throughout northwestern Pennsylvania. News, doctor directory, frequently asked questions (FAQs), employment opportunities, maps and directions.
- Sharon Regional Health System - Sharon Regional provides health care services in northwest Pennsylvania and northeast Ohio through a 288-bed hospital, 20 satellite centers and 1,600 employees.
- St. Luke’s Hospital & Health Network - Provides details of the four hospitals and associated specialty services, as well as a doctor locator, patient information, and testimonials.
- Susquehanna Health System - An alliance of three area hospitals, health centers, and skilled nursing units. Information on services, programs, education and training, physician finder and health resources. Williamsport, Pennsylvania.
- Temple University Health System - Information about the hospitals, physicians and services. Located in Pennsylvania.
- University of Pennsylvania Health System - Health care resources, about the hospitals in the System, research and education information. (Philadelphia)
- UPMC Health System - Integrated not-for-profit healthcare system affiliated with the University of Pittsburgh Schools of the Health Sciences. Physician Directory, Hospital Network, resources.
- Vantage Healthcare Network, Inc. - A system of healthcare providers in Northwestern Pennsylvania. (Meadville)
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